Salvage Cryotherapy for Recurrent Prostate Cancer After Brachytherapy or Radiotherapy
The main objective of this project is to establish a shared comprehensive and systematic protocol for a multicenter prospective registry of patients undergoing salvage cryoablation of the prostate (SCAP). Our study hypothesis is that SCAP constitutes an effective and safe approach to treat local prostate cancer recurrence after brachytherapy or external beam radiation therapy (EBRT).
• Patients with local recurrence (with histological confirmation) after treatment with radiotherapy or brachytherapy without evidence of distant involvement evaluated with PET/PSMA (if not available then Fluciclovine PET/CT or choline PET/CT must be performed).
• Life expectancy \>10 years
• Prostate volume \< 100cc
• PSA\<10 ng/mL
• mpMRI + fusion/systematic biopsy ≤cT3a without affecting the bladder neck or the membranous urethra